Thermo Fisher Scientific PGII Monoclonal Antibody (OTI1H5), TrueMAB
Human Pepsinogen II 단백질을 인식하는 Mouse IgG1 단일클론 항체. Luminex 등 다양한 분석에 사용 가능. 무보존제, 동결건조 형태로 제공되며 재구성 및 결합 실험에 적합. 연구용으로만 사용 가능.
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Applications
- Luminex (LUM): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H5 |
| Immunogen | Native Human Pepsinogen II protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Pepsin is a major proteolytic enzyme secreted by the gastric mucosa. It originates from pepsinogen by removal of a 41-amino-acid segment from the N-terminus. Pepsinogen synthesis occurs in the stomach lining, and hydrochloric acid is required for activation and maintaining optimal acidity (pH 1–3).
Pepsin effectively cleaves peptide bonds involving aromatic amino acids and has broad specificity, favoring phenylalanine and leucine residues. The amino acid composition of Pepsin C differs from pepsinogen and pepsin, particularly in basic amino acids, glutamic acid, aspartic acid, leucine, and isoleucine content.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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