Thermo Fisher Scientific TfR Polyclonal Antibody
Thermo Fisher Scientific의 TfR Polyclonal Antibody는 인간 Transferrin Receptor (CD71)를 표적하는 토끼 유래 IgG 항체입니다. Western blot과 Immunoprecipitation에 사용 가능하며, 액상 형태로 4°C에서 보관합니다. Dog, Horse, Orangutan에서도 반응이 예측됩니다.
- 카탈로그번호
- A304381Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TfR Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 125 to 175 of Human Transferrin Receptor Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Dog, Horse, and Orangutan
Target Information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.
Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome, and in HIV patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: A304-381A-M_Transferrin_Receptor_CD71_P02786-1_Rabbit.svg, A304-381A-M_Transferrin_Receptor_CD71_P02786-1_Rabbit_PDP.jpeg)
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