Thermo Fisher Scientific DCT Polyclonal Antibody
DCT 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DCT (Accession P40126), corresponding to amino acid residues Q56–C106 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853877 |
Product Specific Information
This antibody detects endogenous levels of total TRP2/DCT.
Target Information
The TYR-related proteins, TRP1 and TRP2, are specifically expressed in melanocytes and contribute to melanin synthesis within melanosomes. These proteins share a transmembrane region, contain two metal-binding regions and a cysteine-rich EGF motif, and localize to the melanosomal membrane. Although structurally similar, they have distinct catalytic activities and function together as a multi-enzyme complex, with TRP1 stabilizing TYR expression in melanocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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