Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Chimeric Recombinant Human Monoclonal Antibody (Sb#16)
SARS-CoV-2 스파이크 단백질 RBD 인식용 인간 재조합 단일클론 항체. ELISA 및 기능적 억제 분석에 적합. HEK293 발현, IgM Fc 형식, 액상 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA): Assay-dependent
- Functional Assay (Functional): Assay-dependent
- Inhibition Assays (IA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Human / IgM, Fc |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Sb#16 |
| Immunogen | This clone was originally isolated as a synthetic nanobody (sybody) via a target swap selection procedure against RBD-vYFP using ribosomal display and against RBD-Fc fusion during phage display rounds. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody recognizes and binds the SARS-CoV-2 C-terminal receptor binding domain (RBD) located in the extracellular portion of the spike protein.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The coronavirus Spike (S) protein is critical for viral attachment, fusion, and entry, making it a key target for antibody and vaccine development.
The Spike protein receptor-binding domain (RBD, S-RBD) binds strongly to human and bat ACE2 receptors and exhibits significantly higher affinity than SARS-CoV RBD.
The S1 subunit contains the RBD that specifically interacts with ACE2 receptors on host cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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