
Thermo Fisher Scientific CHST1 Polyclonal Antibody
CHST1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. Human 시료에 반응하며 Protein A로 정제된 액상 형태입니다. CHST1의 N-말단 펩타이드(aa 74-123)를 면역원으로 사용하였으며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.25 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human CHST1 (aa 74–123) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610230 |
Product Specific Information
- Peptide sequence: SFVGQLFNQH LDVFYLFEPL YHVQNTLIPR FTQGKSPADR RVMLGASRDL
- Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Human: 100%
Mouse: 100%
Rabbit: 93%
Rat: 100%
Target Information
Carbohydrate sulfotransferase 1 (CHST1), also known as KSGal6ST or KSST, is a keratan sulfate sulfotransferase predominantly expressed in brain and skeletal muscle, localized to the trans-Golgi network. CHST1 mediates the sulfation of keratan in the cornea, essential for maintaining corneal transparency. It catalyzes the transfer of sulfate groups from 3′-phosphoadenosine 5′-phosphosulfate to position six of galactose residues on keratan sulfate chains, contributing to L-selectin ligand generation. Mutations in CHST1 may be associated with macular corneal dystrophy (MCD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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