Thermo Fisher Scientific CNTNAP1 Polyclonal Antibody
CNTNAP1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간에 반응. N-말단 합성 펩타이드로 면역화된 항체로, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human CNTNAP1 (aa 72–121) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608278 |
Product Specific Information
Peptide sequence:
LQIDLMKKHR IRAVATQGSF NSWDWVTRYM LLYGDRVDSW TPFYQRGHNSSequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 93%
Rabbit: 100%
Rat: 100%
Target Information
CNTNAP1 was initially identified as a 190-kDa protein associated with the contactin-PTPRZ1 complex.
The 1,384-amino acid protein, also designated p190 or CASPR (contactin-associated protein), includes:
- Extracellular domain with several putative protein-protein interaction domains
- Putative transmembrane domain
- 74-amino acid cytoplasmic domain
The architecture of its extracellular domain is similar to that of neurexins, and this protein may serve as the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.
Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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