Thermo Fisher Scientific PGA5 Polyclonal Antibody
Thermo Fisher Scientific의 PGA5 Polyclonal Antibody는 Rat 시료에서 Pepsinogen A 단백질을 검출하기 위한 Rabbit 유래 다클론 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Pepsinogen A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903830 |
Target Information
PGA5 (Pepsinogen 5, group I / Pepsinogen A)
Pepsinogens are inactive precursors of pepsin, a major acid protease in the stomach. Pepsin is a single polypeptide chain enzyme derived from pepsinogen by removal of a 41-amino-acid segment from the N-terminus. It is secreted by the gastric mucosa and requires hydrochloric acid for activation and maintenance of optimal acidity (pH 1–3). Pepsin cleaves peptide bonds involving aromatic amino acids, showing broad substrate specificity. PGA5 belongs to the pepsin family subfamily A1 and is the predominant endopeptidase in vertebrate gastric juice. It is inhibited by ovUS-1, a uterine serpin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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