Thermo Fisher Scientific Inhibin Alpha Polyclonal Antibody
Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능한 Inhibin Alpha 폴리클로날 항체. 토끼 유래 IgG로, 인간, 마우스, 돼지, 랫트 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 생식선 세포 증식 억제 및 종양 억제 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from mouse Inhibin Alpha, amino acids 301–366 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit combines with either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum inhibin levels correlate with granulosa-cell tumor size, making it a useful marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed and undetectable in poorly differentiated tumor cells. Expression varies in gonadal and extragonadal tissues, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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