Thermo Fisher Scientific H1FOO Polyclonal Antibody
H1FOO 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등에 사용 가능. Human, Mouse, Rat에 반응하며, Protein A로 정제된 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human H1FOO (amino acids 81–180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Eukaryotic histones are basic, water-soluble nuclear proteins that form nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn to form chromosomal fibers.
Two molecules each of the four core histones (H2A, H2B, H3, and H4) form the octamer, which consists of two H2A–H2B dimers and two H3–H4 dimers that are nearly symmetrical in tertiary structure.
Over 80% of nucleosomes contain the linker histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher-order chromatin.
H1FOO (H1 histone family, member O, oocyte-specific), also known as OSH1, is a 346 amino acid oocyte-specific histone that localizes to both the nucleus and cytoplasm. Expressed as multiple alternatively spliced isoforms, H1FOO is thought to play an important role in gene control during oogenesis and early embryogenesis and is crucial for meiotic maturation of germinal vesicle-stage oocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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