Thermo Fisher Scientific MEK1/MEK2 Monoclonal Antibody (J.653.9)
MEK1/MEK2 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체로, 인간 및 설치류 등 다양한 종에 반응합니다. Western blot, IHC, ICC/IF, Flow cytometry에 적합하며, 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA515135
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific MEK1/MEK2 Monoclonal Antibody (J.653.9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25 |
| Immunocytochemistry (ICC/IF) | 1:25 |
| Flow Cytometry (Flow) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | J.653.9 |
| Immunogen | Full length MEK1/2 proteins |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_11000214 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003).
In the brain, this pathway also plays a key role in synaptic signaling (Adams and Sweatt, 2002).
Activated MEK1 acts as a dual specificity kinase phosphorylating both threonine and tyrosine residues on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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