Thermo Fisher Scientific RNF182 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: LSSTPVVEFY RPASFDSVTT VSHNWTVWNC TSLLFQTSIR VLVWLLGLLY
• For short term use, store at 2–8°C up to 1 week.
• For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology:
  • Cow: 87%
  • Guinea Pig: 92%
  • Horse: 100%
  • Human: 100%
  • Mouse: 100%
  • Pig: 93%
  • Rabbit: 100%
  • Rat: 100%

Target Information

E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843).
Also involved in the inhibition of TLR-triggered innate immune response by mediating Lys-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.