
Thermo Fisher Scientific F13A1 Monoclonal Antibody (OTI3E3), TrueMAB
인간 F13A1 단백질을 인식하는 Mouse IgG2b 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 동결건조 형태로 제공되며, PBS 완충액(8% 트레할로스) 포함. 연구용으로 혈액 응고 인자 XIII A 서브유닛 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E3 |
| Immunogen | Full length human recombinant protein of human F13A1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen activated in the blood coagulation cascade. Plasma factor XIII consists of two A subunits (catalytic) and two B subunits (carrier). Platelet factor XIII contains only A subunits. Upon thrombin activation in the presence of calcium, plasma factor XIII dissociates its B subunits and forms the active enzyme factor XIIIa.
Factor XIIIa acts as a transglutaminase to catalyze crosslinking between fibrin molecules, stabilizing the clot. It also crosslinks α2-plasmin inhibitor or fibronectin to fibrin α chains. Deficiency of factor XIII can result in bleeding tendencies, poor wound healing, and habitual abortion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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