Thermo Fisher Scientific ALOX5 Monoclonal Antibody (OTI2B7), TrueMAB
인간 ALOX5 단백질(aa 18-364)에 특이적인 Mouse IgG1 단일클론 항체로, Western blot에 1:2,000 희석 비율로 사용 가능. 비접합(Unconjugated) 형태이며, PBS/BSA/glycerol buffer에 보존. 염증 반응 연구 및 leukotriene 합성 관련 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–364 of human ALOX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein which, together with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites implicated in inflammatory responses such as asthma, arthritis, and psoriasis. The protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit its activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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