
Thermo Fisher Scientific ALOX5 Monoclonal Antibody (OTI2C5), TrueMAB
ALOX5 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화됨. 인간 유래 재조합 단백질(aa 18-364)을 면역원으로 사용. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관. 염증 반응 연구 및 류코트리엔 합성 관련 연구용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–364 of human ALOX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites implicated in various inflammatory responses such as asthma, arthritis, and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: TA807011_ALOX5_P09917-1_House_mouse.svg, TA807011_ALOX5_P09917-1_House_mouse_PDP.jpeg)
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