Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), APC, eBioscience
마우스 Ly-6G(Gr-1)를 특이적으로 인식하는 단클론 항체로, 호중구 탐지 및 제거 연구에 적합. APC 형광 표지로 유세포분석(Flow Cytometry)에 최적화. 0.2 µm 여과, 0.2 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Ly-6G Monoclonal Antibody (1A8-Ly6g), APC, eBioscience
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Flow Cytometry (Flow) | 0.5 µg/test | View 29 publications |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse, Rat |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A8-Ly6g |
| Conjugate | APC |
| Excitation/Emission Max | 651/660 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573306 |
Additional Available Formats
- Alexa Fluor 700
- APC-eFluor 780
- Biotin
- Brilliant UV 395 / 563 / 661 / 737
- Brilliant Violet 421 / 480 / 650 / 786
- eFluor 450
- FITC
- Functional Grade
- PE / PE-Cyanine5 / PE-Cyanine7 / PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436 / 600 / 702
- Request custom conjugation
Product Specific Information
Description:
The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G (Gr-1), a 25-kDa GPI protein expressed exclusively by neutrophils. Ly-6G plays a role in neutrophil infiltration, recruitment, and migration, and associates with B2 integrins CD11a and CD11b. Unlike RB6-8C5, this antibody binds only to Ly-6G on neutrophils and can be used for neutrophil depletion with reported antagonist activity.
Applications Reported:
- Suitable for flow cytometric analysis.
Applications Tested:
- Tested by flow cytometric analysis of mouse bone marrow cells.
- Recommended use ≤ 0.5 µg/test (in 100 µL final volume).
- Cell number: 10⁵–10⁸ cells/test (empirically determined).
- Excitation: 633–647 nm; Emission: 660 nm; Laser: Red.
- Filtration: 0.2 µm post-manufacturing filtered.
Target Information
Ly6G (Lymphocyte antigen 6 complex locus G6D) is part of the myeloid differentiation antigen Gr-1 complex with Ly6C. It is a 21–25 kDa protein expressed by myeloid-derived bone marrow cells and serves as a marker for neutrophils, monocytes, and granulocytes. Expression correlates with granulocyte differentiation and maturation. Ly6G is implicated in anti-tumor responses and may modulate local immune activity through inhibitory signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.