Thermo Fisher Scientific RKHD2 Polyclonal Antibody
Human RKHD2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RKHD2. Recombinant protein control fragment (Product #RP-98271) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646588 |
Product Specific Information
Immunogen sequence:
NRLADFSPTS PFSTGNFWFG DTLPSVGSED LAVDSPAFDS LPTSAQTIWT PFEPVNPLSG FGSDPSGNMK TQRRGSQPST PRLSP
Ortholog identity:
- Mouse: 99%
- Rat: 100%
Target Information
Rkhd2 (also known as MEX3C) is a member of a novel family of four homologous human MEX3 proteins, each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module.
MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and cytoplasm via the CRM1 export pathway.
These proteins are evolutionarily conserved RNA-binding proteins involved in post-transcriptional regulation.
Genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8.
Rkhd3 and Rkhd4, but not Rkhd2, co-localize with hDcp1a and Argonaute (Ago) proteins in processing bodies (P bodies), centers of mRNA turnover.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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