Thermo Fisher Scientific RRAS2 Polyclonal Antibody
RRAS2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 ELISA에 적합하며, 인간, 마우스, 랫트 반응성. 액상 형태로 -20°C 보관, 세포막 및 세포질 내 RRAS2 검출에 활용 가능.
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- PA5121063
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- pk
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Thermo Fisher Scientific RRAS2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–204A of human RRAS2 (NP_036382.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914635 |
Product Specific Information
Positive test controls include HT-29, SKOV3, NIH/3T3, Mouse kidney, Mouse heart, Mouse lung, Rat kidney.
The target is typically localized at the cell membrane, cytoplasmic side, and lipid-anchor regions.
Immunogen Sequence:
MAAAGWRDGS GQEKYRLVVV GGGGVGKSAL TIQFIQSYFV TDYDPTIEDS YTKQCVIDDR AARLDILDTA GQEEFGAMRE QYMRTGEGFL LVFSVTDRGS FEEIYKFQRQ ILRVKDRDEF PMILIGNKAD LDHQRQVTQE EGQQLARQLK VTYMEASAKI RMNVDQAFHE LVRVIRKFQE QECPPSPEPT RKEKDKKGCH CVIF
Target Information
RRAS2 is a member of the Ras-related protein family involved in cellular signal transduction. Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS, H-RAS) are key events in cancer development.
RRAS2 (also known as TC21) shares 55–60% amino acid identity with classical Ras proteins and functions as a small GTP-binding protein of the Ras superfamily. It may transduce growth inhibitory signals across the cell membrane through a shared effector with Ras proteins. RRAS2 possesses high oncogenic potential, with overexpression and mutations reported in various tumor tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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