Thermo Fisher Scientific STAM2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human STAM2 (NP_005834.4). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:STAM2,uniProtId:O75886-1,ncbiNodeId:9606,antigenRange:376-525,antigenLength:525,antigenImageFileName:PA5-121061_STAM2_O75886-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121061_STAM2_O75886-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.27 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914633

Product Specific Information

Positive test controls include: MCF7, HepG2, OVCAR3, PC-3. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein.

Immunogen sequence: KLHPPAHYPP ASSGVPMQTY PVQSHGGNYM GQSIHQVTVA QSYSLGPDQI GPLRSLPPNV NSSVTAQPAQ TSYLSTGQDT VSNPTYMNQN SNLQSATGTT AYTQQMGMSV DMSSYQNTTS NLPQLAGFPV TVPAHPVAQQ HTNYHQQPLL

Target Information

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.