Thermo Fisher Scientific CD104 (Integrin beta 4) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Integrins are heterodimers comprised of alpha and beta subunits that form noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes with varying ligand-binding specificities.
Integrins mediate cell–matrix or cell–cell adhesion and transduce signals that regulate gene expression and cell growth.
This gene encodes the integrin beta 4 subunit, a receptor for laminins, which tends to associate with the alpha 6 subunit and plays a pivotal role in invasive carcinoma biology.
Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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