Thermo Fisher Scientific Glutamate Receptor 1 Polyclonal Antibody
Rabbit polyclonal antibody targeting Glutamate Receptor 1 (GluR1). Validated for WB, ELISA, and IP applications. High specificity and affinity purified. Supplied as liquid in glycerol/BSA buffer. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 850–950 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting the chemical signal into an electrical impulse. The receptor desensitizes rapidly and enters a transient inactive state characterized by a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization with delayed accumulation of current flux upon continued glutamate application.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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