Thermo Fisher Scientific KCNIP2 Monoclonal Antibody (OTI2G8), TrueMAB
KCNIP2 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot에 적합합니다. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 공급됩니다. Affinity chromatography로 정제되었으며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G8 |
| Immunogen | Full length human recombinant protein of human KCNIP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain, these channels prevent reverse-propagation of action potentials.
Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate their function.
There are currently three known KChIPs:
- KChIP1: expressed in the brain
- KChIP2: expressed in the brain, heart, and lung; has three isoforms (a, b, c)
- KChIP3: also known as calsenilin and DREAM, expressed in the brain and testis
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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