Thermo Fisher Scientific KCNIP2 Monoclonal Antibody (OTI3C4), TrueMAB
인간 KCNIP2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. TrueMAB 포맷으로 고순도 정제. 심장 및 신경계의 Kv4 채널 연구에 적합. 액상 형태, -20°C 보관.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C4 |
| Immunogen | Full length human recombinant protein of human KCNIP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system.
In the heart, Kv4 channels are involved in the repolarization phase of the action potential, while in the brain they prevent reverse-propagation of action potentials.
KChIPs (Kv channel interacting proteins) are calcium-binding proteins associated with Kv4 channels. They bind to the cytoplasmic amino termini of Kv4 alpha-subunits and modulate their function.
Known members include:
- KChIP1: expressed in the brain
- KChIP2: expressed in brain, heart, and lung (three isoforms: a, b, c)
- KChIP3: also known as calsenilin or DREAM, expressed in brain and testis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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