Thermo Fisher Scientific GHSR Polyclonal Antibody
GHSR 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. IHC(P)와 ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 에너지 항상성과 성장호르몬 분비 조절 연구에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–7.5 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 13 amino acid peptide from N-terminal extracellular domain of human Ghrelin Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550961 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon (100%)
- Monkey, Marmoset (92%)
- Mouse, Rat (85%)
Target Information
Growth hormone secretagogue receptor 1a (GHSR) is a member of the G-protein coupled receptor family. GHSR may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionarily conserved in fish and swine.
Transcript 1a encodes the functional receptor for the Ghrelin ligand, defining a neuroendocrine pathway for growth hormone release. Transcript 1b retains the intron and does not function as a receptor but may modulate isoform 1a activity. Mutations in this gene can cause isolated partial growth hormone deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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