Thermo Fisher Scientific GHSR Polyclonal Antibody
GHSR 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 및 비인간 영장류 시료에 반응합니다. IHC(P)에서 1–3 µg/mL 농도로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 완충액에 0.1% sodium azide가 포함되어 있으며, 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human Ghrelin Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550960 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Baboon, Monkey, Marmoset (100%).
Target Information
Growth hormone secretagogue receptor 1a (GHSR) is a member of the G-protein coupled receptor family. GHSR may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionarily conserved in fish and swine.
One transcript (1a) excises an intron and encodes the functional protein, which is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release.
The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate the activity of isoform 1a. Mutations in the gene can cause isolated partial growth hormone deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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