Thermo Fisher Scientific RASSF10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RASSF10. Recombinant protein control fragment (Product #RP-108350). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RASSF10,uniProtId:A6NK89-1,ncbiNodeId:9606,antigenRange:324-410,antigenLength:507,antigenImageFileName:PA5-83497_RASSF10_A6NK89-1_Rabbit.svg,antigenImageFileNamePDP:PA5-83497_RASSF10_A6NK89-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790650

Product Specific Information

Immunogen sequence: RRCDDLLRLQ EQRVQQEELL ERLSAEIQEE LNQRWMRRRQ EELAAREEPL EPDGGPDGEL LLEQERVRTQ LSTSLYIGLR LNTDLEA

Target Information

RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.