Thermo Fisher Scientific YBX1 Polyclonal Antibody
YBX1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human YBX1. Recombinant protein control fragment (Product # RP-95743) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790646 |
Product Specific Information
Immunogen sequence:
SGEKNEGSES APEGQAQQRR PYRRRRFPPY YMRRPYGRRP QYSNPPVQGE VMEGADNQGA GEQGRPVRQN MYRGYRPRFR RGPPRQRQPR EDGNEEDK
Target Information
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein stabilizes cytoplasmic mRNA and modulates translation by affecting interactions between mRNA and eukaryotic initiation factors. It binds to promoters containing a Y-box sequence (5'-CTGATTGGCCAA-3'), such as HLA class II genes, and regulates transcription of multiple genes. YBX1 promotes DNA strand separation in mismatched or cisplatin-modified DNA, exhibits endonucleolytic activity, and may play a role in DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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