Thermo Fisher Scientific IL-17E Monoclonal Antibody (11K8B1), Biotin
Human IL-17E 단백질에 특이적인 mouse monoclonal antibody. Biotin으로 conjugation되어 있으며 WB, Flow Cytometry, ELISA에 사용 가능. Lyophilized 형태로 제공되며 장기 보관 시 -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Flow Cytometry (Flow) | 1 µg/mL |
| ELISA | 1:10,000–1:50,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 11K8B1 |
| Immunogen | Anti-IL-17E (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17E produced in E. coli followed by hybridoma development. |
| Conjugate | Biotin |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl, 10 mg/mL BSA |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
Store vial at 4°C prior to restoration. Restore with 0.1 mL of deionized water (or equivalent).
For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing.
Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This antibody is specific for human IL-17E protein. A BLAST analysis suggests cross-reactivity with IL-17E from human sources based on 100% homology with the immunizing sequence. Cross-reactivity with IL-17E from other sources has not been determined.
Target Information
Interleukin 25 (IL-25) is a member of the IL-17 family and acts as a proinflammatory cytokine produced by Th17 effector cells. It enables the Th17 subset to initiate or maintain autoimmune processes in diseases such as Rheumatoid Arthritis.
IL-25 induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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