Thermo Fisher Scientific ABHD3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Product Specifications

Product Specific Information

Predicted to react with Mouse samples.

Target Information

The α/β hydrolase superfamily comprises diverse members involved in key biochemical processes and various diseases. Despite having unrelated sequences and different catalytic activities, they share the canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad (histidine, acid, nucleophile).
Members of this superfamily are potential drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.

The ABHD gene subfamily (α/β hydrolase domain containing) includes 15 mostly uncharacterized members, typically utilizing a serine nucleophile forming the G-X-S-X-G motif.

• ABHD1: Metabolizes smoking xenobiotics
• ABHD2: Participates in atherosclerosis development
• ABHD3: 409 amino acid, single-pass type II membrane protein
• ABHD4: Involved in alternative synthesis of N-acyl ethanolamine (NAE)
• ABHD5: Mutations cause Chanarin-Dorfman syndrome
• ABHD6: May play a role in nervous system metabolism and signaling

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

제품 이미지