Thermo Fisher Scientific CHRNG Polyclonal Antibody
CHRNG 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에서 반응합니다. Western blot에 적합하며, 액상 형태로 제공됩니다. PBS/glycerol buffer에 보관하며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA568078
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Acetylcholine Receptor gamma (CHRNG, UniProt ID: P07510-1, antigen range: 31–56, antigen length: 517) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2691940 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein composed of two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit.
The CHRNG gene encodes the gamma subunit, expressed prior to the thirty-third week of gestation in humans. This subunit is involved in neuromuscular organogenesis and ligand binding. Disruption of gamma subunit expression prevents proper receptor localization in cell membranes.
Mutations in this gene are associated with Escobar syndrome and lethal multiple pterygium syndrome. The muscle-type acetylcholine receptor is also the major antigen in the autoimmune disease myasthenia gravis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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