Thermo Fisher Scientific CHRNG Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Product Specifications

Product Specific Information

Predicted to react with Mouse and Rat samples.

Target Information

The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein composed of two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit.
The CHRNG gene encodes the gamma subunit, expressed prior to the thirty-third week of gestation in humans. This subunit is involved in neuromuscular organogenesis and ligand binding. Disruption of gamma subunit expression prevents proper receptor localization in cell membranes.
Mutations in this gene are associated with Escobar syndrome and lethal multiple pterygium syndrome. The muscle-type acetylcholine receptor is also the major antigen in the autoimmune disease myasthenia gravis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.