Thermo Fisher Scientific ATG10 Polyclonal Antibody
ATG10 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. Western blot 및 IHC에 사용 가능하며, 오토파지 관련 연구에 적합합니다. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- OSA00113G-500UG
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from human autophagy-related protein 10 (ATG10, APG10) conjugated to immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: ATG10.
Target Information
ATG10 is involved in autophagy, a process for bulk degradation of cytosolic compartments by lysosomes/vacuoles. The formation of autophagosomes requires dynamic membrane rearrangement, involving two ubiquitin-like modifications: conjugation of APG12p and modification of MAP-LC3 to a membrane-bound form.
APG10 acts as an E2-like enzyme essential for autophagosome formation, mediating ATG12–ATG5 conjugation and MAP-LC3 (MAP1LC3A) modification.
ATG10 is ubiquitously expressed, and the human APG10L gene is localized on chromosome 5q14.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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