Thermo Fisher Scientific extracellular ASIC3 Polyclonal Antibody
ASIC3 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 쥐와 생쥐에 반응하며, 합성 펩타이드(aa 50-100)를 면역원으로 사용했습니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- OSA00114W-100UL
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 50–100 of rat ASIC3 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C for short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in mouse.
- Specificity: ASIC3.
Target Information
Gene: ACCN3
Protein Family: Degenerin/Epithelial Sodium Channel (DEG/ENaC) superfamily
ACCN3 encodes an acid-sensing ion channel that may play an important role in detecting sustained pH changes. Members of this family are amiloride-sensitive sodium channels containing intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop rich in conserved cysteine residues.
A heteromeric association between ACCN3 and ACCN1 forms proton-gated channels sensitive to gadolinium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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