Thermo Fisher Scientific CD49a (Integrin alpha 1) Polyclonal Antibody
CD49a(Integrin alpha 1)에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 무보존제 동결건조 제형. 연구용으로 사용.
- 카탈로그번호
- PA579525
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 0.5–1 µg/mL
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Integrin alpha 1 (1121–1134aa, SNQKRELAIQISKD) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746641 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer functioning as a dual laminin/collagen receptor in neural and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by three divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It contains 28 potential N-glycosylation sites. Human ITGA1 expressed in mouse fibroblast cells appears as a 180-kD protein. ITGA1 is involved in early remodeling of osteoarthritic cartilage and plays a key role in regulating mesenchymal stem cell proliferation and cartilage production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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