Thermo Fisher Scientific CXCL11 Monoclonal Antibody (3C1)

Applications

ELISA (ELISA)

• Tested Dilution: 10 µg/mL

Immunoprecipitation (IP)

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSVKGMAIAL AVILCATVVQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF

Target Information

Interferon-inducible T-cell alpha chemoattractant (I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate.
Its molecular weight is 8–11 kD. I-TAC is also known as CXCL-11 and IP-9.
The cytokine regulates calcium release and induces chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3.
The gene encoding this protein contains 4 exons and at least three polyadenylation signals, which may reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene.
It is upregulated in patients with AIDS, dementia, and multiple sclerosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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