Thermo Fisher Scientific CXCL11 Monoclonal Antibody (3D9)
CXCL11 단백질을 인식하는 Thermo Fisher Scientific의 Mouse IgG2b 단클론 항체(3D9). ELISA에 적합하며 인간 시료 반응성. GST 태그가 포함된 full-length CXCL11 단백질로 면역화. 액상 형태, PBS 버퍼, -20°C 보관.
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Applications
ELISA
- Tested Dilution: 3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D9 |
| Immunogen | CXCL11 (AAH05292, 1–94 a.a) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSVKGMAIAL AVILCATVVQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF
Target Information
Interferon-inducible T-cell alpha chemoattractant (I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas, liver, thymus, spleen, lung, small intestine, placenta, and prostate.
Its molecular weight is 8–11 kDa. I-TAC is also known as CXCL11 and IP-9.
The cytokine regulates calcium release and induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3.
The gene encoding this protein contains 4 exons and at least three polyadenylation signals, which might reflect cell-specific regulation of expression.
IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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