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Thermo Fisher Scientific Desmoglein-2 (DSG2) Monoclonal Antibody ([8E5])
인간 DSG2 단백질을 인식하는 마우스 모노클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 높은 특이성과 재현성을 제공하며, 단백질 A/G로 정제된 고순도 항체. 연구용으로만 사용.
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Thermo Fisher Scientific Desmoglein-2 (DSG2) Monoclonal Antibody ([8E5])
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | [8E5] |
| Immunogen | Recombinant human DSG2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Desmosomes are cell-cell junctions found between epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These desmoglein genes are clustered on chromosome 18. Desmoglein-2 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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