Thermo Fisher Scientific F13A1 Monoclonal Antibody (OTI1H2), TrueMAB
Human F13A1 단백질을 인식하는 Mouse IgG2a 단클론 항체로, WB, IHC(P), ICC/IF 등에 사용 가능. 고순도 Affinity chromatography로 정제된 액상 항체이며, -20°C에서 보관. 연구용으로 혈액 응고 인자 XIII A의 분석에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H2 |
| Immunogen | Full length human recombinant protein of human F13A1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of two A subunits and two B subunits. The A subunits have catalytic function, while the B subunits serve as carrier molecules. Platelet factor XIII consists only of A subunits identical to those in plasma. Upon activation by thrombin and calcium ions, factor XIII becomes factor XIIIa, a transglutaminase that stabilizes fibrin clots by crosslinking fibrin molecules and other proteins such as alpha-2-plasmin inhibitor or fibronectin. Factor XIII deficiency can lead to bleeding tendencies, poor wound healing, and recurrent miscarriage.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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