Thermo Fisher Scientific HSPA1L Monoclonal Antibody (OTI1F12), TrueMAB
Human HSPA1L 단백질(aa 400-641)을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 최적화됨. 액상 형태로 제공되며 PBS, BSA, 글리세롤 버퍼에 보관. 연구용으로만 사용 가능하며 -20°C에서 보관 권장.
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- TA812114
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 400–641 of human HSPA1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cells respond to environmental stress by increasing expression of heat shock proteins (HSPs). The small heat shock proteins (15–30 kDa) are diverse, found as single forms in yeast and human cells, and multiple related forms in plants. Elevated stress protein expression has been linked to neoplasia, including estrogen-induced proteins in breast cancer cells. Hsp27 shows rapid phosphorylation in response to mitogens, tumor promoters, and calcium ionophores. Expression of a 24 kDa estrogen-induced protein correlates with steroid hormone receptor presence and is highly expressed in breast carcinoma. Studies also suggest Hsp27 levels correlate with endometrial adenocarcinomas. Regulation of human Hsp27 by estrogens and heat shock resembles ecdysteroid and heat shock activation of Drosophila Hsp20 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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