Thermo Fisher Scientific HSPA1L Monoclonal Antibody (OTI2H3), TrueMAB
인간 HSPA1L 단백질(aa 400-641)에 특이적인 Mouse IgG1 단일클론 항체. Western blot에 1:2,000 희석으로 검증됨. 액상 형태로 1 mg/mL 농도이며, PBS/BSA/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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- TA812115
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- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 400–641 of human HSPA1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In response to adverse environmental changes, cells from many organisms increase the expression of heat shock proteins. One class, the small heat shock proteins, includes diverse proteins ranging from approximately 15 to >30 kDa. A direct relationship between elevated stress protein expression and neoplasia has been suggested in studies of estrogen-induced proteins in breast cancer cells. Hsp27 shows rapid phosphorylation in response to mitogens, tumor promoters (e.g., phorbol esters), and calcium ionophores. A 24 kDa estrogen-induced protein correlates with steroid hormone receptor expression and is highly expressed in breast carcinoma. Levels of Hsp27 also correlate with endometrial adenocarcinomas. Regulation of human Hsp27 by estrogens and heat shock resembles the ecdysteroid and heat shock activation of Drosophila Hsp20 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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