Thermo Fisher Scientific HSPA1L Monoclonal Antibody (OTI3B10), TrueMAB
Human HSPA1L 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로 Western blot에 최적화됨. E.coli에서 생산된 인간 재조합 단백질(aa 400-641)을 면역원으로 사용. 액상 형태, Affinity chromatography로 정제, -20°C 보관.
- 카탈로그번호
- TA812116
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HSPA1L Monoclonal Antibody (OTI3B10), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 400–641 of human HSPA1L produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In response to adverse environmental changes, many organisms increase the expression of heat shock proteins (HSPs).
Small heat shock proteins (15–30 kDa) exist as single forms in yeast and human cells, and multiple related forms in higher plants.
Elevated stress protein expression has been linked to neoplasia, particularly in estrogen-induced breast cancer proteins.
Hsp27 shows rapid phosphorylation upon exposure to mitogens, tumor promoters (e.g., phorbol esters), and calcium ionophores.
A 24 kDa estrogen-induced protein correlates with steroid hormone receptor expression and is highly expressed in breast carcinoma.
Studies also suggest Hsp27 levels correlate with endometrial adenocarcinomas.
Regulation of human Hsp27 by estrogens and heat shock resembles ecdysteroid and heat shock activation of drosophila Hsp20 genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.