Thermo Fisher Scientific ZCCHC12 Polyclonal Antibody
ZCCHC12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, Human 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZCCHC12. Recombinant protein control fragment (Product #RP-95189). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649825 |
Product Specific Information
Immunogen sequence:
RLPNFLELIR MVREEEDWDD AFIKRKRPKR SESMVERAVS PVAFQGSPPI VIGSADCNVI EIDDTLDDSD EDVILVESQD PPLPSWGA
Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 74%
Target Information
ZCCHC12 is a transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway.
It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex.
It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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