Thermo Fisher Scientific TAGAP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TAGAP. Recombinant protein control fragment (Product #RP-94939). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAGAP,uniProtId:Q8N103-1,ncbiNodeId:9606,antigenRange:292-385,antigenLength:731,antigenImageFileName:PA5-56612_TAGAP_Q8N103-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56612_TAGAP_Q8N103-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648205

Product Specific Information

Immunogen sequence: SLEHTDSSDV STLQNDSAYD SNDPDVESNS SSGISSPSRQ PQVPMATAAG LDSAGPQDAR EVSPEPIVST VARLKSSLAQ PDRRYSEPSM PSSQ

Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 65%.

Target Information

TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein that contains one Rho-GAP domain and exists as 4 alternatively spliced isoforms. TAGAP may function as a GTPase-activating protein and may play important roles during T-cell activation. The gene that encodes TAGAP contains approximately 10,685 bases and maps to human chromosome 6q25.3. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene. Notably, the PARK2 gene, which is associated with Parkinson`s disease, and the genes encoding the major histocompatiblity complex proteins, are also located on chromosome 6. In addition, Stickler syndrome, hydroxylase deficiency and maple syrup urine disease are associated with genes on chromosome 6, while a bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.