Thermo Fisher Scientific PRKAR2A Recombinant Rabbit Monoclonal Antibody (15G8)
PRKAR2A 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, IHC, ICC/IF, Flow Cytometry, ELISA에 적합. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 IgG 형 항체. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 15G8 |
| Immunogen | A synthesized peptide derived from Human PRKAR2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092506 |
Target Information
cAMP is a signaling molecule important for a variety of cellular functions. It activates the cAMP-dependent protein kinase (AMPK), which transduces signals through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes dissociation of the holoenzyme into a dimer of regulatory subunits bound to four cAMP molecules and two free catalytic subunits. Humans have four regulatory and three catalytic subunits of AMPK. The protein encoded by this gene is one of the regulatory subunits, which can be phosphorylated by the activated catalytic subunit and may interact with A-kinase anchoring proteins to determine subcellular localization of AMPK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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