Thermo Fisher Scientific CD66b Recombinant Rabbit Monoclonal Antibody (24H12)
인간 CD66b(CEACAM8)를 인식하는 재조합 토끼 단클론 항체. Flow Cytometry 및 ELISA에 사용 가능. 고순도 친화 크로마토그래피 정제. PBS/50% 글리세롤 완충액에 보관. 연구용 전용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:50–1:200
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 24H12 |
| Immunogen | A synthesized peptide derived from Human CEACAM8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.55 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092589 |
Target Information
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, part of the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in this region.
The encoded protein was originally described as a biliary glycoprotein and later identified as a cell-cell adhesion molecule expressed on leukocytes, epithelia, and endothelia. It mediates adhesion via homophilic and heterophilic interactions and is involved in tissue differentiation, angiogenesis, apoptosis, tumor suppression, metastasis, and immune modulation. Multiple transcript variants encoding different isoforms have been reported, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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