Thermo Fisher Scientific SOCS7 Recombinant Rabbit Monoclonal Antibody (23E4)
인간 SOCS7 단백질을 인식하는 recombinant rabbit monoclonal antibody (clone 23E4). IHC, Flow Cytometry, ELISA 등 다양한 응용에 적합. 고순도 affinity chromatography 정제 및 0.2 mg/mL 농도. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SOCS7 Recombinant Rabbit Monoclonal Antibody (23E4)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23E4 |
| Immunogen | A synthesized peptide derived from Human SOCS7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092538 |
Target Information
SOCS7 regulates signaling cascades through protein ubiquitination and/or sequestration. It functions in insulin signaling and glucose homeostasis by promoting IRS1 ubiquitination and proteasomal degradation. SOCS7 also inhibits prolactin, growth hormone, and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm, and reducing their DNA binding. SOCS7 may act as a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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