Thermo Fisher Scientific GABRA5 Monoclonal Antibody (OTI1G5), TrueMAB
GABRA5 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 IHC(P)에서 사용 가능. 인간 시료 반응성, 무보존제 제형, 동결건조 상태로 공급. 연구용으로 GABA-A 수용체 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–259 of human GABRA5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
GABRA5 is part of the GABA system, a major inhibitory neurotransmitter mechanism in the mammalian brain acting at GABA-A receptors, which are ligand-gated chloride channels.
Chloride conductance can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor.
At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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