Thermo Fisher Scientific UBE2D2 Monoclonal Antibody (OTI1D6), TrueMAB
Human UBE2D2 단백질을 인식하는 Mouse 모노클로날 항체로 Western Blot에 최적화됨. Lyophilized 형태, 1 mg/mL 농도. PBS 버퍼 및 트레할로오스 포함, -20°C 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D6 |
| Immunogen | Full length human recombinant protein of human UBE2D2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The modification of proteins with ubiquitin is a key cellular mechanism for degrading abnormal or short-lived proteins.
Ubiquitination involves three enzyme classes:
- E1: Ubiquitin-activating enzymes
- E2: Ubiquitin-conjugating enzymes
- E3: Ubiquitin-protein ligases
UBE2D2 encodes an E2 ubiquitin-conjugating enzyme involved in ubiquitination of the tumor-suppressor protein p53, induced by an E3 ligase.
Two alternatively spliced transcript variants produce distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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