
Thermo Fisher Scientific Phospho-S6 Ribosomal Protein (Ser240, Ser244) Recombinant Rabbit Monoclonal Antibody (S6RPS240244-CD10), APC
Phospho-S6 Ribosomal Protein (Ser240/244) 항체로, 인간 및 마우스 시료에 반응합니다. HEK293 세포에서 발현된 재조합 토끼 단클론 항체이며, APC로 표지되어 유세포분석(Flow Cytometry)에 적합합니다. 단백질 합성 및 세포 성장 조절 연구에 활용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | S6RPS240244-CD10 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser240/244 of human phospho S6 Ribosomal protein |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897077 |
Additional Formats
- FITC (Cat. No. MA5-37142)
- PE (Cat. No. MA5-37141)
- Custom conjugation available upon request
Target Information
Ribosomes are organelles responsible for catalyzing protein synthesis and consist of a small 40S subunit and a large 60S subunit. These subunits are composed of four RNA species and about 80 distinct proteins. The encoded protein is a component of the 40S subunit and belongs to the S6E family of ribosomal proteins. It is a major substrate for ribosomal protein kinases, with multiple C-terminal serine residues phosphorylated by different kinases. Phosphorylation is induced by growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs during growth arrest. This protein contributes to the control of cell growth and proliferation through selective mRNA translation. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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