Thermo Fisher Scientific DDRGK1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DDRGK1. Recombinant protein control fragment (Product #RP-90580). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DDRGK1,uniProtId:Q96HY6-1,ncbiNodeId:9606,antigenRange:29-98,antigenLength:314,antigenImageFileName:PA5-53049_DDRGK1_Q96HY6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53049_DDRGK1_Q96HY6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640456

Product Specific Information

Immunogen sequence: ASAGQEPLHN EELAGAGRVA QPGPLEPEEP RAGGRPRRRR DLGSRLQAQR RAQRVAWAEA DENEEEAVIL

Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 70%.

Target Information

Protein which interacts with the E3 UFM1-protein ligase UFL1 and one of its substrates TRIP4 and is required for TRIP4 ufmylation. Through TRIP4 ufmylation may regulate nuclear receptors-mediated transcription. May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B. May also play a role in the cellular response to endoplasmic reticulum stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.