Thermo Fisher Scientific IRS-3 Polyclonal Antibody
다중 종 반응성을 가진 Thermo Fisher Scientific의 IRS-3 폴리클로날 항체로, Western blot, IHC, ICC/IF, ELISA 등에 적합합니다. 단백질 A 정제 방식으로 고순도 확보, 안정적인 액상 형태로 -20°C에서 보관 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from rat IRS-3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The family of insulin receptor substrates (IRSs) plays critical roles in signal transduction of various hormones. Four members of the IRS family have been described, each believed to have distinct functions, although their specific physiological roles remain unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor, it binds specifically to cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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