Thermo Fisher Scientific GATA3 Monoclonal Antibody (KT122)
GATA3 단백질을 인식하는 Rat IgG2a 단일클론 항체로 Western blot 및 ELISA에 적합합니다. 마우스 시료 반응성이 있으며 비결합형 액상 형태로 제공됩니다. Protein G 정제, 1 mg/mL 농도, 연구용으로 사용됩니다.
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Thermo Fisher Scientific GATA3 Monoclonal Antibody (KT122)
Applications
- Western Blot (WB): Tested dilution 1:1,000
- Indirect ELISA (reported use)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KT122 |
| Immunogen | Recombinant Mouse Gata3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090702 |
Product Specific Information
This product was used in an Indirect ELISA.
Target Information
The genes for all four subunits of the T-cell antigen receptor (alpha, beta, gamma, and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all four TCR genes.
GATA3, containing a zinc finger domain, is abundantly expressed in the T-lymphocyte lineage and participates in T-cell receptor gene activation through enhancer binding.
Labastie et al. (1994) cloned the human gene and the 5′ end of the mouse gene, showing conservation in zinc finger domains with GATA1.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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